Ning H, Xin ZC, Lin G, Banie L, Lue TF, Lin CS. Effects of icariin on phosphodiesterase-‐5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells. Urology 2006;68:1350–4. 3
Dell'Agli M, Galli GV, Dal Cero E, Belluti F, Matera R, Zironi E, Pagliuca G, Bosisio E. Potent inhibition of human phosphodiesterase-‐5 by icariin derivatives. J Nat Prod 2008;71:1513–7.
Shindel, A. W., Xin, Z.-‐C., Lin, G., Fandel, T. M., Huang, Y.-‐C., Banie, L., Breyer, B. N., Garcia, M. M., Lin, C.-‐S. and Lue, T. F. (2010), Erectogenic and Neurotrophic Effects of Icariin, a Purified Extract of Horny Goat Weed (Epimedium spp.) In Vitro and In Vivo. The Journal of Sexual Medicine, 7: 1518–1528
Oral L-‐citrulline supplementation improves erection hardness in men with mild erectile dysfunction. Source: Urology [0090-‐4295] Cormio yr:2011 vol:77 iss:1 pg:119 -‐22
Darbinyan V, Kteyan A, Panossian A, et al. Rhodiola rosea in stress induced fatigue—a double blind cross-‐over study of a standardized extract SHR-‐5 with a repeated low-‐dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine. 2000;7:365-‐371.
Spasov AA, Wikman GK, Mandrikov VB, et al. A double-‐blind, placebo-‐controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-‐5 extract on the fatigue of students caused by stress during an examination period with a repeated low-‐dose regimen. Phytomedicine. 2000;7:85-‐89.
Shevtsov VA, Zholus BI, Shervarly VI, et al. A randomized trial of two different doses of a SHR-‐5 rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 2003;10:95-‐105.
Olsson EM, von Schéele B, Panossian AG.A randomised, double-‐blind, placebo-‐controlled, parallel-‐group study of the standardised extract shr-‐5 of the roots of Rhodiola rosea in the treatment of subjects with stress-‐related fatigue. Planta Med. 2009 Feb;75(2):105-‐12. Epub 2008 Nov 18.
Soner, et al. Evaluation of vascular smooth muscle and corpus cavernosum on hypercholesterolemia. Is resveratrol promising on erectile dysfunction? Int. J Imp Res, Volume: 22 Issue: 4 Pages: 227-‐233 DOI: 10.1038/ijir.2010.8 Published: JUL-‐AUG 2010
Fukuhara S, Tsujimura A, Okuda H, Yamamoto K, Takao T, Miyagawa Y, Nonomura N, Okuyama A. Vardenafil and resveratrol synergistically enhance the nitric oxide/cyclic guanosine monophosphate pathway in corpus cavernosal smooth muscle cells and its therapeutic potential for erectile dysfunction in the streptozotocin-‐induced diabetic rat: preliminary findings. J Sex Med. 2011 Apr;8(4):1061-‐71. doi: 10.1111/j.1743-‐6109.2010.02193.x. Epub 2011 Jan 26.
Shin S, Jeon JH, Park D, Jang MJ, Choi JH, Choi BH, Joo SS, Nahm SS, Kim JC, Kim YB. Trans-‐Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo. Arch Pharm Res. 2008 Jan;31(1):83-‐7.
Forest CP, Padma-‐Nathan H, Liker HR.; Efficacy and safety of pomegranate juice on improvement of erectile function in male patients with mild to moderate erectile dysfunction: a randomized, placebo-‐controlled, double-‐blind, crossover study. Int J Impot Res. 2007 Nov-‐Dec;19(6):564-‐7. Epub 2007 Jun 14.
Shiota A, Hotta Y, Kataoka T, Morita M, Maeda Y, Kimura K.Oral l-‐Citrulline Supplementation Improves Erectile Function in Rats with Acute Arteriogenic Erectile Dysfunction. J Sex Med. 2013 Jul 11
Moinard C, Cynober L. Citrulline: a new player in the control of nitrogen homeostasis. J Nutr. 2007 Jun;137(6 Suppl 2):1621S-‐1625S.
Cynober L, Moinard C, De Bandt JP.The 2009 ESPEN Sir David Cuthbertson. Citrulline: a new major signaling molecule or just another player in the pharmaconutrition game? Clin Nutr. 2010 Oct;29(5):545-‐51.
Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev. 2006 Fall-‐Winter;24(3-‐4):275-‐90.
Hecker M, Sessa WC, Harris HJ, Anggård EE, Vane JR. The metabolism of L-‐arginine and its significance for the biosynthesis of endothelium-‐derived relaxing factor: cultured endothelial cells recycle L-‐citrulline to L-‐arginine. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8612-‐6.
Al-‐Jarallah A, Igdoura F, Zhang Y, Tenedero CB, White EJ, MacDonald ME, Igdoura SA, Trigatti BL. The effect of pomegranate extract on coronary artery atherosclerosis in SR-‐BI/APOE double knockout mice. Atherosclerosis. 2013 May;228(1):80-‐9.
C. P. Forest, H. Padma-‐Nathan, and H. R. Liker, “Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-‐controlled, double-‐blind, crossover study,” International Journal of Impotence Research, vol. 19, no. 6, pp. 564–567, 2007.
C. B. Stowe, “The effects of pomegranate juice consumption on blood pressure and cardiovascular health,” Complementary Therapies in Clinical Practice, vol. 17, no. 2, pp. 113–115, 2011.
Aviram M, Dornfeld L. 2001. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis 158:195
Davidson MH, Maki KC, Dicklin MR, Feinstein SB, Witchger M, et al. 2009. Effects of consumption of pomegranate juice on carotid intima-‐media thickness in men and women at moderate risk for coronary heart disease. Am. J. Cardiol. 104:936–42
Rock W, Rosenblat M, Miller-‐Lotan R, Levy AP, Elias M, Aviram M. 2008. Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-‐density lipoprotein and stimulates its catalytic activities. J. Agric. Food Chem. 56:8704–13
Sahebkar A.Effects of resveratrol supplementation on plasma lipids: a systematic review and meta-‐analysis of randomized controlled trials. Nutr Rev. 2013 Oct 1.
Frankel EN, Waterhouse AL, Kinsella JE. Inhibition of human LDL oxidation by resveratrol. Lancet. 1993;341:1103–1104. Xia N, Daiber A, Habermeier A, et al. Resveratrol reverses endothelial nitric-‐oxide synthase uncoupling in apolipoprotein E knockout mice. J Pharmacol Exp Ther. 2010;335:149–154.
Cherniack EP, Troen BR. Resveratrol: effects on lipids and cardiovascular risk. Curr Cardiovasc Risk Rep. 2013;7:9–16.
Zhang H, Zhang J, Ungvari Z, et al. Resveratrol improves endothelial function: role of TNFα and vascular oxidative stress. Arterioscler Thromb Vasc Biol. 2009;29:1164–1171.
Chen, X.J.; Ji, H.; Zhang, Q.W.; Tu, P.F.; Wang, Y.T.; Guo, B.L.; Li, S.P. A rapid method for simultaneous determination of 15 flavonoids in Epimedium using pressurized liquid extraction and ultra-‐performance liquid chromatography. J. Pharm. Biomed. Anal. 2008, 46, 226-‐235.
Zhao, F.; Tang, Y.Z.; Liu, Z.Q. Protective effect of icariin on DNA against radical-‐induced oxidative damage. J. Pharm. Pharmacol. 2007, 59, 1729-‐1732.
Liu, Z.Q.; Luo, X.Y.; Sun, Y.X.; Wu, W.; Liu, C.M.; Liu, S.Y. The antioxidative effect of icariin in human erythrocytes against free-‐radical-‐induced haemolysis. J. Pharm. Pharmacol. 2004, 56, 1557-‐1562. Pratico, D. Evidence of oxidative stress in Alzheimer's disease brain and antioxidant therapy: lights and shadows. Ann. N. Y. Acad. Sci. 2008, 1147, 70-‐78.
Nie, J.; Luo, Y.; Huang, X.N.; Gong, Q.H.; Wu, Q.; Shi, J.S. Icariin inhibits beta-‐amyloid peptidesegment 25-‐35 induced expression of beta-‐secretase in rat hippocampus. Eur. J. Pharmacol. 2010, 626, 213-‐218.
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